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J Integrative Medicine 1998;2:56-69
Efficacy of an Integrative Program Including Intravenous and Intramuscular Nutrient Therapies for Arrested Growth
EFFICACY OF AN INTEGRATIVE PROGRAM INCLUDING INTRAVENOUS AND INTRAMUSCULAR NUTRIENT THERAPIES FOR ARRESTED GROWTH

Majid Ali, M.D.; Omar Ali, M.D.;
Alfred Fayemi, M.D.; Judy Juco, M.D.;
Carol Greider-Brandenburger, R.N.;
Mary Ann Carroll, R.N.

Objective
To report the clinical outcome of an integrated management plan, including the use of intravenous and intramuscular nutrient protocols, for restoring growth in six children and adolescents with arrested growth.

Patients
All six patients who presented at the Institute with arrested growth (no gain in height and weight for a period of nine or more months) were included in this study. Two children had stopped growing after chemotherapy (one for rhabdomyosarcoma and the second for Wilms' tumor). Two girls were severely malnourished due to Crohn's disease treated with long-term immunosuppressant therapies. An 11-year-old boy stopped growing after steroid therapy and multiple hospitalizations for Glanzmann's thrombasthenia. The cause of growth arrest in the sixth patient was obscure.
Methods
The integrated management plan included the following: choices in the kitchen designed to provide for optimal hydration, elimination of foods causing incompatibility reactions and rapid glucose-insulin-adrenaline shifts; supplementation with vitamins, minerals, and some redox-restorative substances (RRS) such as glutathione, taurine, selenium; ample herbal support for the bowel, blood, and liver ecosystems; endocrine support when indicated; intramuscular and intravenous nutrient protocols; gentle stretching and noncompetitive (limbic) exercise; and training in effective methods for self-regulation and stress reduction.

Clinical Outcome Measures
Clinical evaluation using general health parameters and measurements of growth parameters. Weight and height measurements before and after institution of the integerated program lasting for a minimum of nine months.

Results
All six children and adolescents showed satisfactory improvement in general health parameters and resumed growth in height and weight (as well as secondary sexual development in two girls) within six to fourteen months of beginning the program.

Conclusion
Preliminary data of this clinical outcome study show efficacy of an integrated plan for restoring growth in children and adolescents with arrested growth and failure to develop secondary sexual characteristics. If validated by larger clinical trials, such a management plan should be of considerable value for growth failure caused by: (1) chemotherapy; (2) steroid and other immunosuppressive therapies for autoimmune disorders; (3) digestive/absorptive disorders; (4) inflammatory disorders of the bowel; (5) certain constitutional disorders; and (6) some cases of arrested growth of obscure origin.


INTRODUCTION

There are no generally accepted management plans for children and adolescents with arrested growth caused by a variety of causes. Special nutritional needs of such children and adolescents are generally ignored except for the wholly inadequate prescriptions of vitamins and minerals in RDA doses. Important issues of battered bowel, blood and liver ecosystems go unrecognized and unaddressed. No serious efforts are made, as attested by the six cases described in this report, to: (1) assess the integrity of the major ecosystems of the body; (2) evaluate the functional nutritional status; (3) address issues of rapid hyperglycemic- hypoglycemic shifts (and the glucose-insulin-adrenaline roller coasters triggered by them); (4) diagnose and manage food sensitivities and mold allergy; (5) consider substituting restorative nutrient and herbal protocols for long-term use of drugs that block one or more membrane receptors, channels, pumps, or inactivate some mediators of physiologic responses; and (6) teach effective self-regulatory methods for relief of local and systemic effects of illness. Indeed, the eleventh edition of Nelson Textbook of Pediatrics does not even mention steroid and chemotherapy- induced severe digestive/absorptive dysfunction as a cause of malnutrition and arrested growth, let alone describe any corrective management plan.1

1 2 3 4 5 6 7 8 9

 

Index of Article Authors
Majid Ali, MD
Omar Ali, MD
Mary Ann Carroll, RN
Alfred Fayemi, MD
C.Grieder-Brandenburger, RN
Judy Juco, MD
Tsuneo Kobayashi MD
Jean A. Monro, MB, BS
(This index is incomplete and will be completed shortly)

Past and
Current Editors
Omar Ali, M.D.
Robert Atkins, M.D.
Robert Bradford, D.Sc
Paul Cheney, M.D., Ph.D.
Steven Davies, M.D.
Alfred O. Fayemi, M.D.
Claus Hanke, M.D.
Doug Hutto, N.D.
Judy Juco, M.D.
Paris Kidd, Ph.D.
Oscar Kruesi, M.D.
Derrick Lonsdale, M.D.
D. Vijen Poleszynski, B.S.
Christine Radulescu, Ph.D.
Ray Russamono, M.D.
Susan Test, Ph.D.
Lowell Weiner, D.D.S.
John C. Williams, M.D.

The Journal of Integrative Medicine shall not be held responsible for statements of the contributing authors. The views and opinions expressed are those of the submitting authors and do not necessarily reflect those of The Journal of Integrative Medicine, The American Academy of Integrative Medicine,
The American Academy of Preventive Medicine, any advertisers or staff members of The Journal of Integrative Medicine
 

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The Journal of Integrative Medicine shall not be held responsible for statements of the contributing authors. The views and opinions expressed are those of the submitting authors and do not necessarily reflect those of The Journal of Integrative Medicine, The American Academy of Integrative Medicine, The American Academy of Preventive Medicine, any advertisers or staff members of The Journal of Integrative Medicine